When used in a static condition, the Micro-Isolator® system functions as an animal-sized Petri dish. The cage may be handled without breaking the cage level microbiological barrier. Although air exchange rates in a static (non-ventilated) Micro-Isolator® may be adequate, ammonia, carbon dioxide and humidity levels can only be regulated with HEPA filtered (99.99% efficient to 0.3 micron particles) air supply systems, such as with individually ventilated cages.
When used in a HEPA filtered condition, each cage is docked on a Ventilated Rack that provides cage level supply and exhaust air ventilation. These systems assure barrier protection for laboratory animals and sustained regulation of airborne particulates, helping protect both animal and personnel. Positive supply air flow is delivered to each cage directly, protecting animals in a HEPA filterd air environment. Cage exhaust air is then captured indirectly as it exits above each cage filter top, assuring barrier protection for personnel.
By practicing appropriate aseptic techniques, the Micro-Isolator® may be opened in a Lab Products laminar flow Stay-Clean™ Workbench that provides Class 100 laminar flow air. Cage changes and animal manipulations may be performed within the workbench without breaking the microbiological barrier from cage to cage.